| Field of application: | Tissue Engineering and Regenerative Medicine/ Nisco Encapsulaton Unit VAR J1 |
| User address: | S.N. Jayasinghe PhD Department of Mechanical Engineering University College London Torrington Place London WC1E 7JE United Kingdom Telephone: +44 (0)2076792960 Fax: +44(0)2073880180 |
Dr. Suwan Jayasinghe (University College London, UCL) - Novel direct strategies to tissue engineering and regenerative medicine:
“Tissue engineering and regenerative medicine classically refers to the ability for building cell-based advanced materials which mimic native tissues. There are several avenues for achieving this but in doing so processing and/or fabrication has been recently seen to take great importance in this endeavour. This has emerged as a result of having the ability to handle living cells (both primary and stem cells) from which biological architectures (specialised to unspecialised) are fabricated for forming a biologically viable microenviroment. These biomicroenviroments can be in the form of either single- or multi-encapsulations, which could also vary from droplets to threads to finally scaffolds containing a heterogeneous population of cells. Such structures containing cells could be explored for developing tissues to possibly organs to even combating human diseases such as diabetes, hormone deficiencies to even cancers. Hence in this endeavour Nisco Engineering AG is in collaboration with the BioPhysics Group based in UCL, where novel direct cell handling approaches are currently explored for exploiting in a wide range of life science based applications. Our collaboration is spearheading the development of several new biotechniques for clinical applications which will have far reaching implications to our wellbeing.”
Selected publications:
- Arumuganathar et al., Biotechnology Journal, DOI: 10.1002/biot.200800170
- Arumuganathar et al., Advanced Materials, DOI: 10.1002/adma.200800911.
- Arumuganathar et al., Soft Matter, 3(2007)605-612
To learn more about the BioPhysics Group at the University College London and Dr. S.N. Jayasinghe please see:
UCL MECHANICAL ENGINEERING Staff Dr Suwan Jayasinghe or
UCL MECHANICAL ENGINEERING Biophysics
Living scaffold and membranes |
Pressure assisted spinning (PAS) |
Microbubble structures |
Pressure assisted spinning (PAS) |
